Viagra fails to work for three out of 10 men, according to Pfizer, the company that makes the drug. It suppresses the enzyme phosphodiesterase type 5 (PDE5), which naturally occurs in erectile tissue. Viagra seemed to work best in women with sexual arousal problems who had previously satisfying sex lives.

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Question from Blue Pal: Does Viagra work for women?. Learn About Erectile Dysfunction (ED) and VIAGRA, an ED Treatment Option. October 22, 1998 -- A new discovery about Viagra could double the drug's popularity. Learn About Erectile Dysfunction (ED) and VIAGRA, an ED Treatment Option. Viagra fails to work for three out of 10 men, according to Pfizer, the company that makes the drug.

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